{"id":1924,"date":"2021-11-24T11:04:29","date_gmt":"2021-11-24T11:04:29","guid":{"rendered":"https:\/\/thesearch.nl\/?p=1924"},"modified":"2023-03-06T12:16:10","modified_gmt":"2023-03-06T12:16:10","slug":"technician-downstream-process-development","status":"publish","type":"post","link":"https:\/\/thesearch.nl\/en\/technician-downstream-process-development\/","title":{"rendered":"Technician Downstream Process Development"},"content":{"rendered":"

Vacature<\/p>\n<\/div>

Technician Downstream Process Development<\/h1><\/div>
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Locatie<\/h2><\/div>
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Amsterdam<\/p>\n<\/div><\/div><\/div>

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Vacature omschrijving<\/h3><\/div>

Work for an Organization that brings innovative therapies to patients worldwide!<\/span><\/p>\n

The Process Development (PD) department is an essential part of the company which is taking the lead for the in-house development, scale-up and manufacture of novel gene therapies. The downstream processing (DSP) team is responsible for the recovery and purification of the biopharmaceutical from the bioreactor harvest through a sequence of unit operations, including cell lysis, filtration, chromatography and UF\/DF. The DSP team will also support tech-transfer to Contract Manufacturing Organisations (CMOs) to support the manufacture of AAV-based gene therapies for clinical trials. \u00a0<\/span><\/p>\n<\/div>

Main responsibilities of the role:<\/h3><\/div>
  • <\/i><\/span>
    As a Technician, you are involved in the practical day-to-day lab work, data analysis and reporting of results<\/div><\/li>
  • <\/i><\/span>
    The Technician prepares, plans and executes experimental work related to Downstream Bioprocessing, such as chromatography and filtration within set timelines; this will be supported by the Scientist Downstream Process Development<\/div><\/li>
  • <\/i><\/span>
    The Technician is involved in the operation and maintenance of small and pilot scale laboratory equipment<\/div><\/li>
  • <\/i><\/span>
    The role will also include time to provide analytical support (analysis of in-process samples and final drug substance) to support development programs<\/div><\/li>
  • <\/i><\/span>
    Communicates the daily work and results obtained to the Scientist Downstream Process Development.<\/div><\/li><\/ul>

    Eisen<\/h3><\/div>
    • <\/i><\/span>
      MSc, or HBO\/BSc, or equivalent, with a minimum of 2 years of relevant working experience<\/div><\/li>
    • <\/i><\/span>
      Hands on experience with small scale chromatography and ultrafiltration equipment required, preferably with AKTA systems<\/div><\/li>
    • <\/i><\/span>
      Familiarity with cell culturing and analytical methods, such as SDS-PAGE, BCA assays, ELISAs is a plus<\/div><\/li>
    • <\/i><\/span>
      You are thorough and have an eye for detail. You deliver highly precise work and work consistently and in a steady pace.<\/div><\/li><\/ul>

      Interested? Apply directly!<\/h3><\/div>